点击科学

2018-01-24 00:26
中国科技教育 2017年7期
关键词:斑马鱼着色抗体

2017-05-26

封面上展示的是木星的南極,图像由“朱诺”号宇宙飞船在52000千米髙空拍摄。图中椭圆形部分是旋风,直径髙达1000千米。通过使用JunoCam摄像仪器在3个独立的轨道上拍摄的多幅图像结合在一起,就可以显示出所有区域的日光、增强色彩及立体投影景象。

Jupiter's south pole, as seen by the Juno spacecraft from an altitude of 52 000 kilometers. The oval features are cyclones, up to 1 000 kilometers in diameter. Multiple images taken with the JunoCam instrument on three separate orbits were combined to show all areas in daylight, enhanced color, and stereographic projection.2017-06-02

封面上展示的是处于三聚体滤过性毒菌表面状态(图中橙色部分)的拉沙病毒糖蛋白,病毒与一个来自于人类幸存者的中和抗体片段(图中白色部分)相结合。如图所示,第2个空抗体结合位点高亮显示。联胞抗体将三聚体中不同的单体桥接在一起,以防止感染所需的构象变化。由Hastie等人确定的晶体结构为疫苗的研制开发提供了一个模板。

The Lassa virus glycoprotein in its trimeric,viral surface state (orange) bound to a fragment of a neutralizing antibody from a human survivor (white). A second, empty antibody binding site is illuminated. Bound antibody bridges different monomers in the trimer to prevent conformational changes required for infection. The crystal structure determined by Hastie et al. provides a template for vaccine development.

2017-06-09

封面上展不的是一个再生的斑马鱼心脏,其受伤后7天的心室顶端(图中底部)。红色着色部分是心外膜细胞层,绿色着色部分是转基因cfefa表达,蓝色着色部分是细胞核。与人类不同,斑马鱼受损的心肌能够在30?60天内再生,而且伤口能愈合成微小的伤疤。从单个细胞到哺乳动物器官系统,疾病和伤害带来的破坏常常是、但不总是通过修复和再生机制解决的。

A regenerating zebrafish heart, 7 days after injury to the apex of the ventricle (bottom).Red stain, epicardial cell layer; green stain, transgenic ctgfa reporter expression; blue stain, cell nuclei. Unlike in humans, lost cardiac muscle regenerates in zebrafish in 30 to 60 days, with minimal scarring. From single cells to mammalian organ systems, the ravages of disease and injury are often, but not always, countered by repair and regeneration mechanisms.

2017-06-16

封面图上展示的是通过艺术手法绘制的量子科学卫星“墨子”。从图中可以看到,2个纠缠态光子被分布到地球上距离约1200千米的2个位置。这种方法比通过光纤直接传输更有效,从而为全球范围内的量子网络,以及太空中的基础量子光学实验开辟了新途径。

Artist's rendering of the quantum science satellite Micius, distributing two entangled photons to two locations separated by 1 200 kilometers on Earth. This approach is much more efficient than direct transmission through optical fibers, thus opening up a new avenue for global-scale quantum networks and foundational quantum optics experiments in space.endprint

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